The first thing to do, of course, is consider whether you want to include auto responders in your marketing mix. You'll need to be sure to find an email marketing provider that supports auto-responder functionality (not all of them do, though Comm100 does support auto-responder functionality). Then, when considering developing an auto responder program, you'll want to consider all of the following points:
The basics we've gone over in this blog post are just the beginning. Keep creating great offers, CTAs, landing pages, and forms — and promote them in multi-channel environments. Be in close touch with your sales team to make sure you're handing off high-quality leads on a regular basis. Last but not least, never stop testing. The more you tweak and test every step of your inbound lead generation process, the more you'll improve lead quality and increase revenue.
I am just writing a new email marketing strategy for my website http://www.professional-cv-writer.co.uk now it’s been re-designed and I have more time to work on my marketing. Having subscribed to numerous blogs, websites, etc. I agree with the poster above, you need to get the number and frequency right. I have often unsubscribed because of the constant barage of emails some organisations send.
Use it to make sales on autopilot. Creating a sales funnel out of an email autoresponder sequence is a widely adopted strategy used by information marketers, but it can also be used by software companies, eCommerce businesses and service providers. For example, it could consist of a series of educational videos, a sales video and follow-ups to sell your information products. Or, you could create a sequence of free educational emails, and then invite them to a live or recorded webinar where you make an offer. For eCommerce businesses, your sales sequence could include promo offers for products your subscriber has just viewed on your website.
In dividing your list in this manner, you give yourself the ability to send more targeted communication. Some customers want both product and sales updates, while others might only want to hear about new versions. If you don’t give them the chance to choose, you risk losing them all-together. Since customers make the best buyers, it’s fairly obvious why you want to keep them subscribed to your customer email list.
Autoresponders are messages set to go out automatically. They help you automate campaigns and manage one-to-one communication with your recipients. They can be sent in a sequence or at intervals, starting from the day a contact signs up to your list e.g. Day 0 (instant message), 3, 7, 14. So, autoresponders are useful if you want to send an automatic message to contacts who join your list. When you set up an autoresponder cycle, messages will go out on a specific day of a contact’s subscription period.
The focus for marketers now is on being in the right place, at the right time, with the right calls to action, in order to capitalize on opportunities to build relationships with these knowledge-empowered consumers, and to give them what they want when they want it. As a rule, marketers recognize this evolution of the lead generation process, but many are faced with the challenge of how exactly to make that shift and execute effectively. 

Don't use CTAs to drive people to your homepage, for instance. Even if your CTA is about your brand or product (and perhaps not an offer like a download), you should still be sending them to a targeted landing page that's relevant to what they are looking for and includes an opt-in form. If you have the opportunity to use a CTA, send them to a page that will convert them into a lead.
Over time, the popularity of email marketing campaigns resulted in personal email inboxes that were overflowing with the latest and greatest offers. Email campaigns grew and people grew tired of them. Laws that allowed customers to unsubscribe breathed new life into email marketing campaigns as customers could easily pick and choose the companies they were interested in.
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