Autoresponders are used by individuals and also by Web sites that need to respond to user comments automatically. For example, an individual may use an autoresponder feature of e-mail to inform the sender that he has gone on vacation and will not be replying personally to e-mails until he returns to the office; an enterprise may use an autoresponder in response to a newsletter subscription request to verify the opt-in or subscription cancellation or to indicate to the sender that a user comment was received. Autorepsonders are also used by enterprises to indicate that an online purchase was processed and will typically include an order confirmation number in the e-mail that is automatically generated and sent to the purchaser.
Unsubscribe rate. Unsubscribes are always going to happen no matter what, and that’s usually OK because those people probably would never have bought from you anyway. However, a high unsubscribe rate can indicate that you are losing potential customers. Check the following: Why did people subscribe to your list in the first place, and are you delivering on that promise? Is the content of your autoresponder highly relevant to the segment it is being sent to? Are you sending too many sales emails with too little value emails?

Over time, the popularity of email marketing campaigns resulted in personal email inboxes that were overflowing with the latest and greatest offers. Email campaigns grew and people grew tired of them. Laws that allowed customers to unsubscribe breathed new life into email marketing campaigns as customers could easily pick and choose the companies they were interested in.
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