With the growth of the internet, the world has changed from one of information scarcity to one of information abundance.  In fact, according to Google chairman Eric Schmidt “there was 5 Exabytes of information created between the dawn of civilization and 2003, but that much information is now created every two days and the pace is rapidly increasing”.  
The first thing to do, of course, is consider whether you want to include auto responders in your marketing mix. You'll need to be sure to find an email marketing provider that supports auto-responder functionality (not all of them do, though Comm100 does support auto-responder functionality). Then, when considering developing an auto responder program, you'll want to consider all of the following points:
Over time, the popularity of email marketing campaigns resulted in personal email inboxes that were overflowing with the latest and greatest offers. Email campaigns grew and people grew tired of them. Laws that allowed customers to unsubscribe breathed new life into email marketing campaigns as customers could easily pick and choose the companies they were interested in.
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